Synbiosis colony counters span one continuous workflow — from simple manual light-pen counting to fully automated, barcode-tracked imaging — so labs can start small and scale up without changing how they count. Every automated model shares the same core approach: illuminated plate imaging paired with counting algorithms tuned to pour plates, spiral plates, chromogenic ID plates, and inhibition zones, replacing subjective manual counts with consistent, reproducible results.
Scalable automation, one counting workflow
Every Synbiosis colony counter is built on the same core methodology – from a simple manual light-pen counting stage to a fully robotic, barcode-tracked imaging pipeline. Labs can start small and scale up to walk-away automation without ever changing how they count.
Illuminated plate imaging
Sub-stage LED illumination – and on automated models, three-colour RGB or epi/transmitted lighting – creates high-contrast images so colonies of varying size, shape, and colour can be reliably distinguished from background and media artefacts.
Intelligent counting algorithms
Automated systems use image-analysis algorithms tuned to pour plates, spiral plates, chromogenic ID plates, dilution series, and inhibition zones, replacing subjective manual counts with consistent, reproducible results.
Data traceability & compliance
Automated models export results directly to Excel, PDF, or LIMS, with 21 CFR Part 11-compliant audit trails and user access control – built for regulated GLP/GMP microbiology workflows.
Compare the Synbiosis colony counter portfolio side by side to find the ideal solution for your microbiology laboratory. From affordable manual counting to fully automated high-throughput systems with barcode tracking, zone measurement, and 21 CFR Part 11 compliance, each instrument delivers fast, accurate, and reproducible colony analysis for research, clinical, food, pharmaceutical, and industrial applications.
| Feature / Instrument | aCOLade 2 | aCOLyte 3 HD | Protos 3 | ProtoCOL 3 | ProtoCOL 3 HDE | AutoCOL |
|---|---|---|---|---|---|---|
| Automation Level | Manual | Entry automated | Automated | Automated | Automated (HD) | Fully automated |
| Max Plate Diameter | 90 mm | 90 mm | 100 mm | 150 mm | 100 mm | Multi-plate handling |
| Colony Counting | ✓ | ✓ (pour + spiral) | ✓ | ✓ | ✓ | ✓ |
| Zone Measurement | - | - | - | ✓ | ✓ (±0.175 mm) | - |
| Barcode / Plate Tracking | - | - | - | - | ✓ | ✓ |
| 21 CFR Part 11 Compliant | - | - | - | ✓ | ✓ | ✓ |
| Data Export | - | Excel / Open Office | Excel / PDF / LIMS | Excel / PDF / LIMS | Excel / PDF / LIMS | Excel / PDF / LIMS |
| Typical Use Case | Teaching / budget labs | Routine automated counting | High-speed counting | Counting + zone measurement | Precision zone measurement | High-throughput unattended testing |
Used by leading institutions driving scientific progress across India and globally.
The aCOLyte 3 HD is Synbiosis’ entry-level automated colony counter, designed for immediate usability with plug-and-play USB connectivity and an intuitive interface — a natural first step up from manual counting on the aCOLade 2.
The aCOLade 2 is a manual colony counter using a light pen and digital display, with no imaging or automation. The aCOLyte 3 HD automates the process entirely, using a camera and LED illumination to automatically count colonies on both pour and spiral plates, then export results to Excel or OpenOffice.
Choose ProtoCOL 3 or ProtoCOL 3 HDE when your workflow includes antimicrobial susceptibility testing or other inhibition zone assays. Both automate zone measurement alongside colony counting, with the ProtoCOL 3 HDE delivering the highest precision available in the range, at ±0.175 mm accuracy.
ProtoCOL 3 is a versatile, modular platform supporting colony counting, zone measurement, spiral plate analysis, eAST, and Ames tests on plates up to 150 mm. The ProtoCOL 3 HDE is a more specialized, higher-precision system focused on colony counting and zone measurement with an HD camera and RGB lighting, delivering ±0.175 mm zone accuracy and detecting colonies as small as 30 µm — the finest available in the range.
The AutoCOL is purpose-built for high-throughput, hands-free operation, processing up to 100 plates within one hour via automatic plate loading, barcode scanning, imaging, and counting — ideal for labs that need to free up operator time while maintaining full 21 CFR Part 11 traceability.
ProtoCOL 3, ProtoCOL 3 HDE, and AutoCOL all offer full 21 CFR Part 11 compliance, with secure data management, audit trails, and controlled user access, suited to regulated GLP/GMP microbiology environments.
Protos 3 uses a fixed-modular software design covering pour plates, spiral plates, chromogenic ID plates, and dilution series, with one-click operation for high-volume labs needing fast, consistent results across diverse sample types.
Medispec India is the exclusive channel partner of Synbiosis laboratory equipment, providing local sales, installation, certification, and service support.